Label-free silicon-photonics cytometry · application surface

What the chip can tell a clinician — and a bioprocess engineer

Every readout in the tiered biomarker list, mapped to what it enables — by hardware tier, clinical or industrial setting, and how strong the evidence is. Start with the full map, or open a focused read on CGT & CAR-T, oncology, or sepsis triage — each split honestly into what is possible and what is not. Tier 1 is the validated reagent-free layer; Tier 2 is predicted virtual staining; Tier 3 is the reagent-based roadmap. Pre-hardware — computational + published-literature stage, not diagnostic claims.

Tier
Evidence
Setting
Validated — published label-free basis, >95% on core classes Emerging — Tier 1, medium / adjunct Predicted — Tier 2, research-stage Roadmap — Tier 3, reagent-based
No applications match those filters.

Where the chip goes blind

A cytometer measures cells — their size, structure, mechanics and (at Tier 3) surface markers. It does not measure soluble chemistry, nucleic acids or tissue. These are the hard edges that keep every claim above honest.